7 for Dummies
Daughters et al. (2009) offered evidence which the expanded CTG repeat from the ATXN8OS gene is transcribed into an mRNA by having an expanded CUG repeat, conferring a poisonous gain of function that plays a job inside the SCA8 phenotype. In brain tissue from humans and mice with SCA8, ATXN8OS mRNA made up of the expanded repeat was located to buil